Geriatric Psychiatry Neuroimaging Laboratory

Late Life Depression

Depression can occur at any stage in life, including older age. Depression that occurs in later life can pose distinct challenges, particularly with regard to treatment. Although treatment response to medication can take up to 8 weeks, neuroimaging data during the initiation of medication may help predict who will respond to medication. This research program is designed to identify brain responses to medication and see how they predict remission of depressive symptoms.

Relevant Publications

MRI Predictors of Treatment Response in Late-Life Depression
Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters

Depression Resources

Older Adults and Depression